The Science of ProBiora3®
Decades of Research. One Patented Blend.
ProBiora3 is the result of more than 35 years of research into the oral microbiome and the beneficial bacteria naturally found in healthy mouths. Developed by oral microbiologist Dr. Jeffrey Hillman, ProBiora3 represents a different approach to oral health—one focused on supporting beneficial bacteria as part of a healthier oral environment.
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The Discovery
It Started with a Simple Question.
What if oral health could be supported by replenishing beneficial bacteria naturally found in healthy mouths?
That question led Dr. Jeffrey Hillman and his team to spend decades studying the oral microbiome and identifying bacterial strains associated with healthy teeth and gums.
Their research ultimately led to the development of ProBiora3 - a patented probiotic blend designed specifically for the oral environment.
A timeline of discovery:
- 1980s - Dr. Hillman identifies beneficial bacteria native to teeth and gums
- 1990s-2000s - Strains validated; FDA FRAS status and patents secured
- 2009 - ProBiora product line launches as first true oral care probiotic
- Today - 35+ years of research. One-of-a-kind science. Patented. Proven.
35+
YEARS
of oral microbiome research
3
PATENTED STRAINS
combined in the ProBiora3 blend
2+
BILLION CFU
delivered in every powerful tablet
1
DAILY TABLET
simple to use.
easy to maintain
The ProBiora3 Blend
Three Strains. One Purpose.
ProBiora3® combines three beneficial bacterial strains originally identified in healthy mouths and selected specifically for the oral environment.
Together, they form the patented blend that powers every ProBiora product.
- Streptococcus oralis KJ3® - Targets the gum line and tongue to fight gum disease while safely whitening teeth with natural hydrogen peroxide.
- Streptococcus uberis KJ2® - Works deep within oral tissues to clear out stubborn, odor-causing bacteria and enhance your breath's freshness.
- Streptococcus rattus JH145® - Bonds to tooth surfaces to crowd out cavity-causing bacteria without producing harmful, enamel-eroding acids.
Meet the Scientist
The Vision Behind ProBiora3
Jeffrey D. Hillman, DMD, PhD devoted his career to studying the oral microbiome and the beneficial bacteria naturally found in healthy mouths.
His pioneering research helped establish a new way of thinking about oral health—one focused on supporting beneficial bacteria as part of a healthier oral environment.
Today, that work lives on through ProBiora3® and the products powered by its patented blend.
Dr. Jeffrey Hillman:
- Oral Microbiologist & Research Pioneer
- Inventor of ProBiora Technology
- Professor Emeritus at the University of Florida College of Dentistry
- 35+ Years of Oral Microbiome Research
