Why ProBiora Is Different
The Right Probiotics in the Right Place.
Not all probiotics are designed for the mouth. ProBiora3® contains beneficial bacteria originally isolated from healthy mouths and selected specifically to support the oral microbiome. By supporting balance where oral health begins, ProBiora helps promote healthier teeth and gums, fresher breath, and a whiter smile.
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Different Probiotics, Different Purposes
Not All Probiotics Are Designed to Work in the Same Place.
Different probiotics are developed to support different areas of the body. Some are selected for digestive health. Others are designed for throat support.
ProBiora3 was developed specifically for the oral environment using beneficial bacteria originally isolated from healthy mouths and selected for their ability to thrive where oral health begins - on teeth and around the gums.
Because probiotics work best when they're designed for where they belong.
- Gut Probiotics — Designed for digestive health and gut balance
- Throat Probiotics — Designed for throat support and upper respiratory health
- ProBiora3® — Designed specifically for teeth, gums, and the oral microbiome
Competitive Comparison
ProBiora is the only oral probiotic with strains isolated from the teeth & gums.
ProBiora3® strains come from the surfaces they’re designed to support — healthy human teeth and gums.
★ The Original
ProBiora ProfessionalProBiora Health | 
Advanced Oral ProbioticsGreat Oral Health | 
Oral Health ProbioticsNatureWise | 
Dental ProbioticReplenish The Good | 
Oral ProbioticsRestore | 
PRO-DentalHyperbiotics | 
Dental ProbioticSuperTeeth | 
ProdentisBioGaia | |
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| Native to Teeth & Gums | Yes | No | No | No | No | No | No | No |
| Probiotic Strains |
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- ProBiora3®
- S. oralis KJ3®
- S. uberis KJ2®
- S. rattus JH145®
Other oral probiotics
- BLIS K12™
- BLIS M18™
- L. paracasei
- L. reuteri
- L. acidophilus
- L. plantarum
- L. salivarius
- S. thermophilus
- BLIS K12™
- BLIS M18™
- L. casei
- L. plantarum
- L. rhamnosus GG
- L. salivarius
- B. breve
- B. infantis
- S. thermophilus
- BLIS K12™
- BLIS M18™
- L. paracasei
- L. reuteri
- BLIS K12™
- BLIS M18™
- L. paracasei
- L. reuteri
- L. acidophilus
- S. thermophilus
- BLIS K12™
- BLIS M18™
- L. paracasei LPC-37®
- L. reuteri
- BLIS K12™
- BLIS M18™
- L. paracasei
- L. reuteri
- L. salivarius
- L. acidophilus
- L. reuteri DSM 17938
- L. reuteri ATCC PTA 5289
ProBiora3® — the only clinically studied probiotic blend sourced directly from healthy human teeth and gums.
Why ProBiora Stands Apart
Beneficial bacteria originally isolated from healthy mouths and selected for the oral microbiome.
Designed to work on tooth surfaces and around the gums, where oral health begins.
Supports beneficial bacteria and helps maintain a healthier oral microbiome.
Created specifically for the mouth rather than adapted from gut probiotics.
From the Mouth, For the Mouth
Originally Discovered in Healthy Teeth and Gums.
Unlike probiotics developed for other parts of the body, ProBiora3® contains beneficial bacteria originally identified in healthy mouths.
These strains were selected specifically for the oral environment and work together to help support a balanced oral microbiome.
But what makes them different isn't just where they came from - it's where they're designed to work.
Designed to support the areas where oral biofilm naturally forms:
- Tooth Surfaces — Where oral biofilm naturally forms
- Along the Gumline — Where oral biofilm commonly accumulates
- Gum Pockets — Where bacteria-driven concerns begin
"The mouth has its own microbiome, and it deserves its own probiotics."
— Lora Hooper, BSDH, RDH, EFDA
Complete Your Routine
Beyond Brushing and Flossing.
Brushing, flossing, and rinsing help remove buildup from the surface of your teeth. ProBiora adds another layer of support by helping replenish beneficial bacteria in the mouth and support a healthier oral microbiome.
It's a simple daily step that fits easily into the routine you already have.
- Brush — Remove buildup and plaque from tooth surfaces
- Floss — Clear buildup between teeth and along the gumline
- ProBiora — Replenish beneficial bacteria and support a healthier oral microbiome
