Our Huge Seasonal Deals Are Here!

Smile Bright for the Holidays!

Get ready for holiday gatherings with smiles that make a great first impression! ProBiora probiotics freshen breath, whiten teeth, and support gum and tooth health for all ages – even your pets. Prepare for the season by signing up for a 25% discount on all ProBiora product subscriptions and keep your oral health covered all year.

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Time to Upgrade Your Oral Care!

Welcome to the Power of Positive Bacteria

ProBiora’s patented oral-care probiotics repopulate your mouth’s good bacteria while crowding out the bad, giving you whiter teeth, fresher breath, and healthier teeth and gums – all in a simple, once daily tablet.

Replenish. Repopulate. Rebalance.

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ProBiora oral-care probiotics contain the ONLY strains isolated from the teeth and gums of a healthy adult. In contrast, other oral-care probiotics typically include strains of bacteria that are native to the throat or gut, not the mouth.

Patented and Precise

Targeted Science From the Mouth, For the Mouth

ProBiora is the only probiotic that contains ProBiora3®, a patented blend of the three strains of beneficial bacteria that naturally lives on your teeth and below your gums. Other oral-care probiotics only include strains of throat or gut bacteria.

Something Everyone Can Smile About

There’s a ProBiora for You…
And the Whole Family (Furry Ones too!)

Whether looking for yourself, your kids, your patients, or even your pets, there’s a ProBiora specifically formulated to improve gum and tooth health, freshen breath, and whiten teeth. Shop our entire lineup of patented oral-care probiotics!

The Original Oral-Care Probiotic

Backed by 30 Years of Clinical Research

Landmark oral health research led by microbiologist Jeffrey D. Hillman, DMD, PhD, and a team or researchers, along with 30 years of other clinical research, led to the development of ProBiora probiotics. Taken daily, our probiotics provide a proactive approach to help restore and maintain oral health.

Featured Products

ProBiora

ProBiora Kids

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Pro Strength

ProBiora
for Dogs

ProBiora
for Cats

Your Journey to a Healthier Mouth Starts with a Single Step


A simple, revolutionary once daily tablet added to your normal oral-care routine… Oh, by the way, it ends there too.

Maybe you’ve tried it all… toothpaste, mouthwash, flossing. But no matter what you do, you still deal with oral health issues. Could just be bad breath, or maybe a less-than-white smile, or even something more serious. No matter what oral-health issue you might be dealing with, there’s only one truly effective way to address it. And that’s by dealing with the culprit, bad bacteria. The best way to deal with bad bacteria is to bring back the good, by using probiotics specifically meant for your mouth.

ProBiora repopulates that good bacteria, which crowds out the bad bacteria behind bad breath, cavities, and gum issues like gingivitis, periodontitis, oral inflammation and bleeding gums.

How to Add ProBiora to Your Routine

To add the Power of ProBiora to your oral-care regimen, follow these simple steps.

Make It A Bedtime Ritual

You can take ProBiora at any time of day and achieve results, but taking ProBiora at bedtime is more effective to repopulate that good bacteria.

Give It Time

After brushing your teeth, chew and swish the tablet for 30 seconds or simply let the tablet dissolve on your tongue to allow for the probiotics to get to work.

Gargle, Wait, Dissolve

Mouthwash kills all bacteria, including the good. So, if you use mouthwash, wait 30 minutes and then take ProBiora to replenish that good bacteria in your mouth.

Experience the Difference

In as little as 30 days, ProBiora has repopulated the good bacteria, crowding out the bad, and leaving you with healthier teeth and gums, fresher breath, and whiter teeth.

Not All Probiotics Are Created Equal

ProBiora stands out in the oral-care probiotic market because its’ product line contains ProBiora3®, a patented blend of three strains of beneficial bacteria naturally found in the mouth. These strains are specifically designed to inhabit the oral environment, living on teeth and below the gums, which is crucial for maintaining oral health. By populating the mouth with these beneficial bacteria, ProBiora’s probiotics help to crowd out harmful bacteria, thereby restoring the natural balance of the oral microbiome and promoting healthier teeth and gums.

In contrast, other oral-care probiotics typically include strains of bacteria that are native to the throat or gut, not the mouth. This distinction is significant because bacteria thrive best in their natural environment. Hence, only bacteria that originate from the mouth can effectively colonize and flourish in the oral cavity. By using mouth-specific bacteria, ProBiora ensures that its probiotics are optimally suited to improve and maintain oral health.

The Healthy Mouth Experts


With 35 plus years of oral-care probiotic research under our belts, what makes a health mouth is our specialty.

Landmark oral health research led by microbiologist Jeffrey D. Hillman, DMD, PhD, and a team or researchers, along with 30 years of other clinical research, led to the development of ProBiora probiotics. Taken daily, our probiotics provide a proactive approach to help restore and maintain oral health.

The Leading Experts all Agree: Not only is ProBiora dentist-recommended, but we actually rely on top dental professionals to advise us on our full line of products. This Dental & Medical Professional Advisory Council helps ensure we deliver the highest quality oral-care products possible.

Why ProBiora is Right for You and Your Family

Benefits You Can Feel

ProBiora’s line of probiotics naturally fill the mouth with the beneficial bacteria it needs for healthier teeth and gums, crowding out the harmful bacteria and restoring the mouth’s natural balance leaving it feeling cleaner and fresher everyday.

The Proof is in the Patent

With a proprietary and patented blend of three naturally occurring strains of beneficial bacteria, ProBiora offers the only probiotics that specifically target and live on your teeth and gums. It’s a game changer

The Mouth/Body Connection

Your mouth is the gateway to your body, from what you eat to what you drink… even what you breathe. If your mouth isn’t healthy, you won’t be healthy. It’s really that simple.

For Your Pet’s Oral Health Too!

Dog breath? Cat breath? We can help. Your pet’s mouth has unique needs, so we made a product just for them. Just sprinkle the powder on their food once a day, and keep their mouth healthy and smelling fresher.

Healthy Mouths and Happy Customers

My dentist recommended my taking this product for a month, to see how it would reduce the bacteria/anaerobes in my gums/tartar sample. I saw him today, and there was nothing on the slide!!! All organisms eliminated!!!

I noticed a huge difference in the way my mouth felt and my breath smelled after only one night’s use. I am now three weeks in and I have a noticeable decrease in inflammation and my gums are more pink than ever!

My dogs have used ProBiora for Dogs since they were puppies; they are now 7 and 8 years old. Their dental health is amazing. As a dental hygienist this is important to me. I recommend it to everyone!